|Study Type||Randomized Clinical Trial|
|Estimated Enrollment||1300 participants|
|Intervention Model||Parallel Assignment|
|Intervention Model Description||Randomization to distal transradial access or conventional transradial access. Both techniques are standard of care.|
|Masking||None (Open Label)|
|Primary Purpose||Supportive Care|
|Actual Study Start Date||December 10, 2019|
Primary Outcome Measures
Forearm radial artery occlusion (RAO) rate before discharge
[Time Frame: up to 5 days] Forearm radial artery occlusion (RAO) rate before discharge measured with Doppler Ultrasound
Primary endpoint result: RAO at discharge
Exceptionally low incidence of RAO at discharge in both groups, the lowest ever reported in any multicenter TRA trial. Those results support clinical application of best practice recommendations for the reduction of RAO.
Patent hemostasis was achieved in 94.4% of patient in the TRA group.
Secondary endpoint result
support distal radial access as a valid alternative to conventional radial access, with simpler & shorter hemostasis.
equally low forearm RAO rates with conventional & distal radial access, highlighting the importance and clinical benefits of a rigorous protocol for RAO prevention.
Glidesheath Slender™ to apply lower-profile system necessary to complete the procedure.
TR Band™ to achieve patent hemostasis, with minimal pressure strategy together with short hemostasis time.
Learn more about DISCO RADIAL from the Primary Investigators
Adel Aminian, Gregory A Sgueglia, Marcus Wiemer, Gabriele Luigi Gasparini, Joelle Kefer, Zoltan Ruzsa, Maarten A H van Leeuwen, Bert Vandeloo, Claudiu Ungureanu, Sasko Kedev, Juan F Iglesias, Gregor Leibundgut, Karim Ratib, Ivo Bernat, Irene Barriocanal, Vladimir Borovicanin, Shigeru Saito, Distal Versus Conventional Radial Access for Coronary Angiography and Intervention (DISCO RADIAL)