Usefulness of Hydrogel-Coated Coils in Embolization of Pulmonary Arteriovenous Malformations¹

Overview

To evaluate the usefulness of hydrogel-coated coils for preventing recanalization after coil embolization of pulmonary arteriovenous malformations (PAVMs).

Study Design

  • Retrospective analysis of 37 consecutive patients with 57 previously untreated PAVMs between Jan 2013 and Jun 2017.
  • Mean age of patients was 49 years (range 9-83 years).
  • Median size of the feeding artery was 3.7mm (range 1.5-6.1mm).
  • Median size of the venous sac was 9.3mm (range 2.6-36.6mm).
  • For all PAVMs, embolization was performed using hydrogel-coated coils with or without other coils. 
  • Recanalization was evaluated with time-resolved magnetic resonance angiography and/or pulmonary angiography (TR-MRA).

Result

Result of Usefulness of Hydrogel-Coated Coils about clinical evidence of Azur (image)

 

Two feeding arteries embolized using hydrogel-coated coils (image)

Two feeding arteries embolized using hydrogel-coated coils

TR-MRA at 21 months after coil embolization shows no recanalization (image)

TR-MRA at 21 months after coil embolization
shows no recanalization

Reprinted from Cardiovascular and interventional radiology vol 41, (2018) : 848-855.

Conclusion

Hydrogel-coated coils may be useful to reduce the occurrence of recanalization after the embolization of PAVMs.